100% inspection of pharmaceutical product
The PULSAR Headspace Inspection System is an automated 100% inspection machine designed to measure headspace oxygen, moisture, and carbon dioxide levels in sealed parenteral containers. PULSAR characterizes the physical headspace conditions of a container in a single compact and flexible platform.
Aseptic manufacturing facilities implement various analytical systems and inspection processes to ensure the quality of finished product and to monitor production processes. The PULSAR Headspace Inspection System has been designed to address the following applications:
• Headspace oxygen monitoring during the filling of oxygen-sensitive formulations
• 100% moisture inspection of freeze dried product
• Automated media fill inspection
Headspace Laser Spectroscopy
The PULSAR Headspace Inspection System uses a patented laser-based detection method developed with funding from the Food and Drug Administration. Light from a near infrared laser is passed through a container in the region above the product and below the cap (headspace region). Diode laser sensors are designed to monitor the absorption wavelength of the target headspace molecules to determine headspace concentrations. Vials that do not meet the specified headspace conditions can then be identified and rejected. This measurement method allows for the rapid analysis of 100% of product while reducing testing costs.
LIGHTHOUSE Instruments introduced the laser headspace technology into the pharmaceutical industry more than 15 years ago and has the largest installed base of laser-based headspace systems worldwide.
