The FMS-Moisture/Pressure Headspace Analyzer is a non-destructive gas analyzer for simultaneously monitoring moisture partial pressure and total headspace pressure. This compact benchtop instrument utilizes a patented laser absorption technique developed with funding from the Food and Drug Administration.
Light from a near-infrared diode laser is tuned to match an internal absorption frequency of the water molecule and passed through the empty container headspace above the product. The amount of laser light absorbed is proportional to the moisture concentration in the headspace and the width of the absorption profile gives the total headspace pressure. The measurement method is rapid and non-destructive. These characteristics allow for multiple measurements on the same sample enabling the accurate monitoring of the moisture and total headspace pressure of a single sample over time. Because the sample is not destroyed there are no waste disposal issues and potentially valuable product can be saved for other tests.
The analyzer is a robust solid state device and is straightforward to use. Operators do not require special expertise to run the system meaning the accuracy of the measurements does not depend on operator skill.
The benchtop headspace moisture/pressure analyzer is used for development and QC laboratory applications as well as the final inspection of headspace moisture and pressure levels in production and/or packaging. Systems can be permanently situated in laboratories for product development, release testing, and QC investigations or mounted on carts and wheeled from line to line for in-process monitoring and troubleshooting activities.
Applications include:
• Vacuum leak detection
• Container closure integrity studies
• Moisture determination of lyo product
• Lyo chamber moisture mapping
• Water vapor permeation studies
• Moisture degradation studies
• Stability trends, end-of-shelf life studies
New Generation FMS Demonstration
